BDBM81462 (R)-Trihexyphenidyl::(S)-Trihexyphenidyl::Benzhexol::CAS_58947-95-8::NSC_5572::TRIHEXYPHENIDYL HYDROCHLORIDE::Trihexyphenidyl

SMILES OC(CCN1CCCCC1)(C1CCCCC1)c1ccccc1

InChI Key InChIKey=HWHLPVGTWGOCJO-UHFFFAOYSA-N

Data  22 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 81462   

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  5.01nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  15.9nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  676nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataIC50:  10nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank